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Features Plus

✔Not affected by antibiotics. Recommended to take alongside them.Not affected by antibiotics. Recommended to take alongside them.Strongest product on the market. 20 Billion CFU/g

✔Improve digestive wellbeing and digestive immune function.

✔Acts to reduce inflammatory compounds and increase the production of anti-inflammatory compounds in the body.

✔Supports digestive system health by helping to restore good intestinal flora and maintaining and re-building gastrointestinal mucosal membrane health.

✔Helps maintain or restore a healthy balance of gut bacteria by inhibiting harmful microbes and promoting beneficial ones.

✔Reduces symptoms like diarrhea, bloating, and abdominal pain by modulating gut inflammation and microbial balance.

✔May help manage conditions like ulcerative colitis by reducing intestinal inflammation and supporting mucosal healing.

✔Helps in reducing overgrowth of harmful bacteria in the small intestine.

✔Releases compounds that inhibit the growth of harmful bacteria and toxins in the gut.

Ingredients Plus

Saccharomyces boulardii (20 billion CFU per capsule)

Directions & Storage Plus

give according to your pet’s weight or as recommended by your animal healthcare professional. Can be given with or without food.

0-10kg – 1 capsule daily

15-30kg – 1.5 capsules daily

Over 30kg – 2 capsules daily

Cats – Give ½ - 1 capsule daily

Keep out of reach of children

Store below 25 degrees Celsius.

Keep in a cool dry place out of direct sunlight. Keep container tightly closed.

Cautions Plus

Use with caution in pregnant or lactating animals as safe use in pregnant and lactating animals has not been established.

The Science Plus

D'Angelo S, Fracassi F, Bresciani F, Galuppi R, Diana A, Linta N, Bettini G, Morini M, Pietra M. Effect of Saccharomyces boulardii in dog with chronic enteropathies: double-blinded, placebo-controlled study. Vet Rec. 2018 Mar 3;182(9):258. doi: 10.1136/vr.104241. Epub 2017 Dec 6. PMID: 29212912.

Garrigues Q, Mugnier A, Chastant S, Sicard F, Martin JC, Svilar L, Castex M, Ramis-Vidal MG, Rovere N, Michaud L, David P, Mansalier E, Rodiles A, Mila H, Apper E. The supplementation of female dogs with live yeast Saccharomyces cerevisiae var. boulardii CNCM I-1079 acts as gut stabilizer at whelping and modulates immunometabolic phenotype of the puppies. Front Nutr. 2024 Apr 12;11:1366256. doi: 10.3389/fnut.2024.1366256. PMID: 38680531; PMCID: PMC11048480.

Meineri G, Martello E, Atuahene D, Miretti S, Stefanon B, Sandri M, Biasato I, Corvaglia MR, Ferrocino I, Cocolin LS. Effects of Saccharomyces boulardii Supplementation on Nutritional Status, Fecal Parameters, Microbiota, and Mycobiota in Breeding Adult Dogs. Vet Sci. 2022 Jul 28;9(8):389. doi: 10.3390/vetsci9080389. PMID: 36006304; PMCID: PMC9414249.

Pais P, Almeida V, Yılmaz M, Teixeira MC. Saccharomyces boulardii: What Makes It Tick as Successful Probiotic? J Fungi (Basel). 2020 Jun 4;6(2):78. doi: 10.3390/jof6020078. PMID: 32512834; PMCID: PMC7344949.

Whittemore JC, Moyers TD, Price JM. Randomized, controlled, crossover trial of prevention of antibiotic-induced gastrointestinal signs using a synbiotic mixture in healthy research dogs. J Vet Intern Med. 2019 Jul;33(4):1619-1626. doi: 10.1111/jvim.15553. Epub 2019 Jul 3. PMID: 31268578; PMCID: PMC6639531.

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